Best Vitamin B6 Supplements Reviews & Ratings

Disclosure: We use affiliate links and may receive a small commission on purchases.

In a Hurry? Editors choice:
1. Solgar
Test Winner: 1. Solgar

Vitamin B6 is a member of vitamin B complex which includes all the water-soluble vitamins apart from vitamin C. Other members of the complex include thiamine (B1), riboflavin (B2), niacin (B3), pantothenic acid (B5), biotin, folic acid and cobalamins (B12). All these members were once thought to be a single nutrient, but later, scientists discovered that each had a unique structure and function.

Solgar
  • Solgar
  • 5 out of 5
    Our rating
  • Affordable
  • Price: See Here
Integrative
  • Integrative
  • 4.6 out of 5
    Our rating
  • Hypoallergenic
  • Price: See Here
Now Foods
  • Now Foods
  • 4.3 out of 5
    Our rating
  • Quality
  • Price: See Here

Vitamin B6 was discovered in 1934 by a scientist known as Paul Gyorgy, as a coincidence when he was studying skin diseases in rats. In 1938 it was isolated, and in 1939 it was given its other name, pyridoxine. In 1957, there were significant advancements in the study of vitamin B6, and it is the year that the daily required levels were established.

It plays a key role in many biological reactions, metabolic processes, brain functioning and it strengthens the immune system. We can obtain it from both plant and animal sources. However, in situations like pregnancy, advanced age, chronic alcoholism, when taking oral contraceptives, or when on a high protein diet, one may not be able to meet the added demands. Hence the need for supplementation.

Failure to meet the meet the daily requirements can cause vitamin B6 deficiency which can pose health problems. It may lead to peripheral neuropathies, microcytic anemia, conjunctivitis, skin wounds, depression, confusion, seizures, irritability and poor growth in children.

If you need to supplement your diet, vitamin B6 is available in the dietary supplements’ market both as a multivitamin and a stand-alone vitamin. The B6 supplements are available as either tablets, capsules or in liquid form.

Vitamin B6 occurs in three forms—pyridoxal, pyridoxine, and pyridoxamine. All three can be converted to the coenzyme PLP (pyridoxal phosphate). Pyridoxine in the form of pyridoxine hydrochloride is the most common in supplements, though some products also contain PLP.

In this review, we have comprehensively written about ten of the best vitamin B6 products that we carefully evaluated using our pre-determined criteria. Here are the ten products that we hand-picked for you.

10 Best Vitamin B6 Supplements

1. Solgar

1. Solgar
Solgar has vegetarian tablets each 25mg of active vitamin B6 in the form of pyridoxine HCL. The tablets are formulated to be free of gluten, wheat, and dairy. The product is a certified non-GMO that is also free of artificial flavors, sweeteners, preservatives, and colors.
Expand to see more

Features/Specifications

  • In tablet form
  • Each tablet is 25mg
  • Active ingredient is pyridoxine HCL 25mg
  • Free of all artificial colors, preservatives and gluten.
  • Each bottle has 100 tablets

Directions for use:

Take one to two tablets daily, preferably with a meal.

Price/Value

Solgar's tablets are in the lower price range and still quality, safe and effective.

Verdict

Vitamin B6 is hard to find in the low doses, but Solgar solves the problem. It comes in 25mg which is what is recommended for morning sickness. Even better, they are small and easy to swallow.

Pros
  • Small easy to swallow tablet
  • Non-GMO
  • Affordable
  • Low dosage suitable for morning sickness
  • Few side effects
  • Nice glass bottle packaging
  • Suitable for vegetarians
Cons
  • Not coated so has an unpleasant taste

2. Integrative Therapeutics

2. Integrative Therapeutics
Integrative Therapeutics'S capsules are a complex formula with added other B vitamins. They are suitable for vegetarians, are pure, and hypoallergenic. They have no sugar, salt, yeast, wheat, gluten, soy, or dairy. They are also free of artificial colors, preservatives and animal products.
Expand to see more

Features/Specifications

  • In capsule form
  • Are a complex of B vitamins
  • Suitable for vegetarians
  • Pure and hypoallergenic
  • Free of artificial colors, preservatives, and animal products
  • Certified NSF product for sports
  • Active ingredients are Riboflavin, Thiamin, Vitamin b6, Niacin, Vitamin b12, Biotine, among other.
  • Each bottle has 60 capsules

Recommendations for use:

take one or two tablets daily, preferably with meals

Price/Value

They are slightly pricey but worth if you want a superior product that is effective, hypoallergenic and made to the highest possible standards in an FDA approved facility. Moreover, the B6 is combined with other members of the B complex to make it more effective.

Verdict

These supplements may cost you more, but you will be sure that they are a great value product. From the user reviews, we are convinced that the capsules are a great buy. They work fast, use superior ingredients and have fewer side effects.

Pros
  • Pure and hypoallergenic
  • Contains other vitamin Bs
  • Suitable for vegetarians
  • Easily absorbed and metabolized
  • Low dose of vitamin B6
  • Effects seen within a short period
Cons
  • Unpleasant smell

3. NOW Foods

3. NOW Foods
Now vitamin B6 supplement is in the form of pyridoxine HCL. Each tablet has 100mg of the active ingredient. The tablets are screened for potency and purity. Also, they contain no sugar, salt, yeast, gluten, corn, soy, milk, egg, shellfish or preservatives.
Expand to see more

Features/Specifications

  • In capsule form
  • Active ingredient is pyridoxine HCL 100mg
  • Inactive ingredients are rice flour and gelatin for the capsule
  • Hypoallergenic
  • No artificial additives except the capsule
  • Screened for potency and purity
  • Each bottle has 250 capsules

Recommendations for use:

take one capsule daily, preferably with food

Price/Value

These tablets are incredibly priced if you consider the bottle contains 250 tablets which can last you for about eight months if you are taking one tablet per day. They are easy on the pocket, and if you buy them, they will serve you for a long time.

Verdict

If you need your B6 supplements in high doses, then Now Foods product is the best choice. The capsules are also affordable, and the quality is guaranteed. They are pure vitamin B6 with no binders and fillers, so you will be getting most of the drug without consuming unnecessary ingredients.

Pros
  • Quality is guaranteed through independent testing
  • No artificial binders and fillers
  • Free of potential allergens
  • Affordable
  • Good reputation company
  • Takes a short period to show results
Cons
  • A little bit strong thus can have some side effects

4. Nature Made

4. Nature Made
Nature Made pyridoxine is in tablet form, each containing 100mg of active ingredients. In addition to vitamin B6, it contains 30mg of calcium to enhance its absorption and bioavailability. The tablets have no artificial colors, flavors, preservatives, yeast, starch or gluten.
Expand to see more

Features/Specifications

  • In tablet form
  • Each tablet is 100mg
  • Each bottle has 100 tablets
  • Free of artificial colors, preservatives, and flavors
  • Gluten free
  • No yeast or starch
  • Pyridoxine hydrochloride 100mg, Calcium carbonate 30mg

Directions for use:

take one tablet daily with a meal. Preferably, ingest water before taking it, while taking and after swallowing.

Price/Value

Nature Made vitamin B6 tablets are very fairly priced considering that they are 100 tablets and have a good reputation for effectiveness.

Verdict

Not only is this product affordable but also, has small easy to swallow tablets. They also have a good reputation not only for B6 tablets but other nutritional supplements. The drawback is that they are bitter. You can deal with this by taking with a lot of water or another beverage of your choice.

Pros
  • Affordable
  • Small tablets
  • Easy to swallow
  • Has a reliable reputation
  • Free of preservatives, coloring, and flavors
  • Gluten free
Cons
  • Very bitter

5. Pure Encapsulations - P5P 50

5. Pure Encapsulations - P5P 50
Pure Encapsulations capsules have 50mg of vitamin B6 in the form of pyridoxal 5’ phosphate (P5P), which is the activated form. The tablets are certified to be gluten-free and free of allergens, GMOs, environmental contaminants, and artificial additives. For quality, the capsules are independently tested for potency and purity. The capsules are also hypoallergenic and suitable for a vegetarian diet.
Expand to see more

Features/Specifications

  • In capsule form
  • Suitable for vegetarians
  • Are hypoallergenic
  • Independently tested for purity and potency
  • GMO free
  • Certified gluten-free product
  • Active ingredient is pyridoxal 5' phosphate 50 mg (activated B6)
  • Each bottle has 60 vegetarian capsules

Directions for use:

take two tablets per day, in divided doses with a meal.

Price/Value

Pure Encapsulation is reasonably priced considering that the capsules are effective and their quality and purity are guaranteed.

Verdict

There is nothing that beats the feeling that you get when taking something that you are sure is safe. Pure Encapsulations B6 supplements are an excellent buy for this reason. It is independently tested for validation of potency and purity. So, when buying it, you are sure that it is effective. From the users, the capsules work well and have very few unwanted effects.

Pros
  • Contains the active form of vitamin B6
  • Hypoallergenic
  • Certified non-GMO and gluten-free product
  • Purity and potency is guaranteed through independent testing
  • Easily absorbed
  • Few side effects
Cons
  • Causes stomach discomfort

6. EZ Melts

6. EZ Melts
Ez Melts B6 supplements are in the form of chewable tablets. They are fast in melting and give an orange blast effect in the mouth. For them to be pleasant, they are naturally flavored, sweetened and colored. Once chewed, they are quickly absorbed and utilized by the body tissues. They are free of gluten, artificial sugars, and dye. Ez Melts is also a non-GMO product.
Expand to see more

Features/Specifications

  • Are chewable tablets
  • Are fast melting in the mouth
  • Naturally flavored, sweetened and colored
  • Easily absorbed from the gastrointestinal tract
  • Active ingredient is pyridoxine HCL 50mg
  • Free of artificial sugar, gluten, and dye
  • Non-GMO product
  • Each bottle has 60 tablets

Directions for use:

take two tablets per day.

Price/Value

Ez Melts tablets are reasonably priced considering that they are pleasant to taste, efficient and have servings that can last you for two months.

Verdict

If you dislike swallowing tablets, then Ez Melts product is a great choice for you. The tablets are chewable, easily melt once in the mouth and you do not need any water to swallow them. You can even dissolve them in a drink of your choice. They are easily absorbed once in the stomach, so they start working immediately. They are flavored, colored and sweetened with natural products, so you do not have to worry about artificial additives and sugars.

Pros
  • Great in taste
  • Melt rapidly in the mouth so no need for water
  • Easily absorbed
  • Suitable for kids if prescribed
  • Flavored and sweetened with natural products
Cons
  • Big tablets

7. Nature's Bounty

7. Nature's Bounty
Nature’s Bounty's supplement comes intablets which have vitamin B6 in the form of pyridoxine hydrochloride. It is a USA-made product that is suitable for vegetarians and can be used as a dietary supplement. Each tablet has 100mg of the active ingredient, which is high enough for prevention and treatment of vitamin B6 deficiency.
Expand to see more

Features/Specifications

  • In form of uncoated tablets
  • Active ingredient is pyridoxine hydrochloride 100mg
  • Suitable for vegetarians
  • No artificial color, flavor, sweetener, preservatives, sugar or starch
  • Free of lactose, soy, gluten, wheat, yeast, fish, sodium, and nuts
  • Each bottle has 100 tablets
  • Directions for use:

    take one tablet daily preferably with a meal.

    Price/Value

    Nature’s Bounty B6 tablets are very pocket-friendly. A single bottle comes with a supply of more than three months. There is also a choice to pick packs of two or four bottles. The number of pills per bottle is eye-catching and totally worth buying if you need them in a dose of 100mg.

    Verdict

    For treatment and prevention of vitamin B6 deficiency, Nature’s Bounty is a good selection for its dosage. Furthermore, the product is affordable, suitable for vegetarians and easy to swallow.

Pros
  • Suitable for vegetarians
  • Free of most potential allergens
  • No artificial additives, colors or preservatives
  • Works well within a short period
  • Dose is high enough to prevent and treat deficiencies
Cons
  • Unpleasant taste and smell

8. Carlson Labs

8. Carlson Labs
Carlson Labs vitamin B6 is in a liquid form. The B6 vitamin is in the form of pyridoxine hydrochloride. Each serving (one-half teaspoonful) has about 100mg of vitamin B6. It also contains about seven calories and 1.5 grams of carbohydrates, per serving.
Expand to see more

Features/Specifications

  • In liquid form
  • Active ingredient is pyridoxine hydrochloride 100mg
  • Is free of milk, soy, wheat, yeast, corn, and sugar
  • Suitable for vegetarians
  • Each bottle has 48 servings

Directions for use:

take one-half teaspoon per day, preferably at mealtime. Can also be mixed with other liquids like water, smoothie, or juice.

Price/Value

This option is fairly priced for a bottle that has about 48 servings that can last you for more than a month.

Verdict

If you dislike tablets and capsules, then this product is one of the best choices. It is in liquid form which you can take plain or add to a beverage of your choice. Liquids are also easy for kids to take as you can sneak the supplement in their drinks and if they can stand them plain, they are easy to swallow.

Pros
  • Easy to take
  • Can be mixed with other fluids
  • Easily absorbed
  • Suitable for vegetarians
  • Sweetened with natural ingredients
Cons
  • Has a strong taste

9. Best Naturals

9. Best Naturals
Best Naturals B6 is another product that is excellent for use in pregnancy, in case of nausea and vomiting. The tablets are low in dosage (25mg per tablet). The vitamin B6 is in the form of pyridoxine hydrochloride. The supplements are made in the USA in accordance with Good Manufacturing Practices (GMP), and purity and potency are guaranteed. The tablets have no flavors, artificial color, preservatives, or sweeteners. They are also free of most of the potential allergens.
Expand to see more

Features/Specifications

  • In uncoated tablet form
  • A USA-made product
  • cGMP compliant
  • Purity and potency tested
  • Active ingredient is pyridoxine hydrochloride 25mg
  • Each tablet has 250 tablets
  • Free of flavor, preservatives, artificial colors, sweetener, starch, corn, sugar, soy, egg, milk lactose, gluten, wheat, sodium, yeast, and fish.

Directions of use:

take one to three tablets daily at mealtimes.

Price/Value

For a supply of 250 tablets of each capsule, these tablets are greatly priced. They are extremely easy on the pocket, and one bottle will serve for the entire prescribed period.

Verdict

Best Naturals B6 supplements are a great buy not just for the price but also for the low dosage. 25mg dosage is hard to find yet, it is safe in pregnancy for nausea and vomiting. The supply of more than eight months is also another factor to consider.

Pros
  • Purity and potency guaranteed
  • Free of most potential allergens
  • Free of artificial ingredients
  • Easy to take
  • Low dose
  • Fewer side effects
  • Can help with morning sickness
Cons
  • Uncoated so has an unpleasant chalky taste

10. Designs for Health

10. Designs for Health
Designs for Health is another great B6 vitamin product that comes in liquid form. Vitamin B6 is combined with magnesium and zinc. It is a non-GMO product that is free of soy, toxins, and gluten. The product is also GMP compliant, FDA regulated, and NSF certified. The tablets have also undergone independent lab tests for quality checks.
Expand to see more

Features/Specifications

  • In liquid form
  • Suitable for vegetarians
  • Non-GMO
  • cGMP compliant
  • Free of gluten, soy, and toxins
  • Independently tested for potency
  • Has both pyridoxine HCL and pyridoxal 5 phosphate
  • Has zinc and magnesium
  • Each bottle has about 24 servings
  • Each serving has 50mg of vitamin B6

Directions for use:

take 5ml (one teaspoon) per day.

Price/Value

Designs for Health vitamin B6 is a bit pricey for only 24 servings, but it is worth for its quality, taste, and purity.

Verdict

If you want a great tasting product, then Designs for Health is an excellent pick. It has a natural fruity flavor and taste that is easy for children and in pregnancy. Please note that for kids and in pregnancy or when breastfeeding, you need a prescription. The liquid supplement is also manufactured to the best possible standards. You may have to pay a little more, but you will be assured of quality and safety.

Pros
  • Has a natural raspberry flavor
  • Easy to take
  • Easily absorbed
  • Quality is guaranteed through independent testing
  • Suitable for vegetarians
  • Non-GMO
Cons
  • Contains aspartame


The author and the publisher present all contained information for educative purposes only. Read carefully all product packaging and instructions for any services or products mentioned or suggested on this website and observe all safety instructions. For more information, read our Disclaimer.